MIC 205 Microbiology. (3) F, S, SS
Basic course for persons without credit in BIO 181, emphasizing general principles; role of microorganisms in health, ecology, and applied fields. May not be used for Microbiology major credit unless a diagnostic test is passed. Prerequisites: BIO 100 (or BOT 108) and CHM 101 or instructor approval. General Studies: S2 (if credit also earned in MIC 206).

MIC 206 Microbiology Laboratory. (1) F, S, SS
Principles and laboratory techniques used in identifying and handling microorganisms. 3 hours lab. Pre- or corequisite: MIC 205 or 220. General Studies: S2 (if credit also earned in MIC 205).

MIC 220 Biology of Microorganisms. (3) F, S
Basic course for persons with credit in BIO 181. Detailed study of microbial cells, their structure, genetics, physiology, and taxonomy. Corequisites: BIO 182; CHM 115.

MIC 302 Advanced Bacteriology Laboratory. (2) F, S
Advanced laboratory techniques in bacterial growth, physiology, genetics, microscopy, and basic virology. Required of Microbiology majors. 4 hours lab. Prerequisites: completion of L1 requirement and either A or B. (A) MIC 206 and 220 or (B) MIC 205 and 206 and instructor approval. General Studies: L2 (if credit also earned in MIC 401).

MIC 360 Bacterial Physiology. (3) F
Mechanisms and control of cell metabolism, structures, and functions. Prerequisite: MIC 220. Pre- or corequisite: CHM 361 or instructor approval.

MIC 381 Pathogenic Microbes. (3) S
Host-microbial interactions in infectious disease, with emphasis on pathogenesis, host defenses, and molecular mechanisms of microbial virulence. Prerequisite: MIC 360 or 6 hours of microbiology with instructor approval.

MIC 401 Research Paper. (1) F, S, SS
A paper of 15 or more pages based on library or laboratory research in collaboration with a faculty member. Required of all Microbiology majors. Prerequisites: MIC 302; completion of L1 requirement. General Studies: L2 (if credit also earned in MIC 302).

MIC 420 Introductory Immunology. (3) F
Fundamental concepts in research and medicine. Cellular immunity, antibody and antigen, immunogenetics, immunoregulation, hypersensitivity, clinical immunology, and nervous-immune system interactions. Prerequisites: CHM 231 (or 331) and MIC 205 (or 220) or instructor approval.

MIC 421 Experimental Immunology. (2) S
An introduction to the basic techniques, methods, and assays used in immunology. 6 hours lab. Prerequisites: CHM 231 and 331 and MIC 302 or instructor approval.

MIC 425 Advanced Immunology. (3) S '98
A survey of recent advances in immunology, including lymphocyte membranes, lymphokines/biochemistry, molecular genetics, theoretical immunology, immunoregulation, neuroimmunology, and immunologic diseases. Prerequisite: MIC 420 or instructor approval.

MIC 441 Bacterial Genetics. (3) S
Survey of genetic exchange and regulatory processes in bacteria and their viruses. Bacteria and viruses as tools in genetic engineering. Prerequisites: BIO 340 and MIC 205 (or 220) or instructor approval.

MIC 442 Bacterial Genetics Laboratory. (1) F
Techniques of mutagenesis, mapping, and strain construction. 4 hours lab. Prerequisites: MIC 206, 302. Pre- or corequisite: MIC 441.

MIC 470 Bacterial Diversity and Systematics. (3) F
Enrichment culture, biology, and classification of the nonpathogenic bacteria. 1 hour lecture, 6 hours lab. Prerequisite: MIC 302.

MIC 485 General Virology. (3) F
Fundamental nature of viruses, their replication, pathogenesis, and ecology. Prerequisites: BIO 340 and CHM 331 or instructor approval.

MIC 486 General Virology Laboratory. (2) N
An introduction to the growth, assay, and detection of viruses. 6 hours lab. Prerequisite: MIC 302. Pre- or corequisite: MIC 485.

MIC 527 Neuroimmunology. (3) S '97
Studying mind's influence on immunity and the immune system's influence on the mind, neuroimmunologic diseases, and the neuroimmunological circuitry involved. Seminar. Prerequisite: MIC 420 or instructor approval.

MIC 530 Bacterial Differentiation. (3) N
Molecular biology of sporulation and germination in bacteria. Emphasis on the control of cellular differentiation. Prerequisite: BIO 543 or MIC 441 or instructor approval.

MIC 545 Recombinant DNA Methodology. (3) N
Principles of genetic engineering using in vitro DNA recombination; characteristics of plasmid and phage vectors; recombinant selection and physical characterization. Prerequisites: BIO 543; MIC 441; instructor approval.

MIC 546 Recombinant DNA Laboratory. (2) N
Basic techniques in isolation of chromosomal, plasmid, and bacteriophage DNA; transformation; gene-splicing methods. Corequisite: MIC 545.

MIC 581 Molecular Mechanism of Pathogenesis. (3) F
Pathogenic mechanisms and host responses in bacterial diseases. Prerequisites: MIC 381 and 420 or instructor approval.

MIC 585 Molecular Virology. (3) S '98
Selected topics concerning molecular aspects of eukaryotic virus replication and pathogenesis. Prerequisite: instructor approval.

MIC 591 Seminar. (1–3) F, S
Topics may be selected from the following:

(a)	Bacterial Ecology
(b)	Current Research in Microbiology
(c)	Enzymology
(d)	Genetic Engineering
(e)	Genetics
(f)	Immunology
(g)	Molecular Virology
(h)	Neuroimmunology
(i)	Pathogenic Bacteriology

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