MIC 205 Microbiology. (3)
fall, spring, summer
Basic course for students without credit in BIO 181, emphasizing general principles; role of microorganisms in health, ecology, and applied fields. May not be used for Microbiology major credit unless a diagnostic test is passed. Prerequisites: both BIO 100 (or PLB 108) and CHM 101 or only instructor approval.
General Studies: SG (if credit also earned in MIC 206)

MIC 206 Microbiology Laboratory. (1)
fall, spring, summer
Principles and laboratory techniques used in identifying and handling microorganisms. 3 hours lab. Fee. Pre- or corequisite: MIC 205 or 220.
General Studies: SG (if credit also earned in MIC 205)

MIC 220 Biology of Microorganisms. (3)
fall and spring
Basic course for students with credit in BIO 181. Detailed study of microbial cells, their structure, genetics, physiology, and taxonomy. Corequisites: BIO 182; CHM 115.

MIC 302 Advanced Bacteriology Laboratory. (2)
fall and spring
Advanced laboratory techniques in bacterial growth, physiology, genetics, and microscopy. Required of Microbiology majors. 4 hours lab. Fee. Prerequisites: completion of General Studies L requirement and either A or B. (A) MIC 206 and 220 or (B) MIC 205 and 206 and instructor approval.
General Studies: L (if credit also earned in MIC 401)

MIC 360 Bacterial Physiology. (3)
fall and spring
Mechanisms and control of cell metabolism, structures, and functions. Prerequisite: MIC 220. Pre- or corequisite: BCH 361 or instructor approval.

MIC 380 Medical Parasitology. (3)
fall
Parasitic diseases of humans, including life cycle events and clinical manifestations. Prerequisite: MIC 205 or 220.

MIC 381 Pathogenic Microbes. (3)
spring
Host-microbial interactions in infectious disease, with emphasis on pathogenesis, host defenses, and molecular mechanisms of microbial virulence. Prerequisite: MIC 360 or 6 hours in microbiology with instructor approval.

MIC 401 Research Paper. (1)
fall, spring, summer
Paper of 15 or more pages based on library or laboratory research in collaboration with a faculty member. Required of all Microbiology majors. Prerequisites: MIC 302; completion of General Studies L requirement.
General Studies: L (if credit also earned in MIC 302)

MIC 420 Immunology: Molecular and Cellular Foundations. (3)
fall
Molecular and cellular foundations of immunology. Antibody/antigen interactions, cellular response, cytokines, immunogenetics, immunoregulation, autoimmunity, psychoneuroimmunology research/medical perspectives. Prerequisites: both CHM 231 (or 331) and MIC 205 (or 220) or only instructor approval.

MIC 421 Experimental Immunology. (2)
fall and spring
Introduction to the basic techniques, methods, and assays used in immunology. 6 hours lab. Fee. Prerequisites: a combination of CHM 231 and 331 and MIC 302 or only instructor approval.

MIC 425 Advanced Immunology. (3)
spring in odd years
Survey of recent advances in immunology, including lymphocyte membranes, lymphokines/biochemistry, molecular genetics, theoretical immunology, immunoregulation, neuroimmunology, and immunologic diseases. Prerequisite: MIC 420 or instructor approval.

MIC 441 Bacterial Genetics. (3)
spring
Survey of genetic exchange and regulatory processes in bacteria and their viruses. Bacteria and viruses as tools in genetic engineering. Prerequisites: both BIO 340 and MIC 205 (or 220) or only instructor approval.

MIC 442 Bacterial Genetics Laboratory. (1)
not regularly offered
Techniques of mutagenesis, mapping, and strain and genetic library construction. 4 hours lab. Prerequisites: MIC 206, 302. Pre- or corequisite: MIC 441.

MIC 445 Techniques in Molecular Biology/Genetics. (2)
fall and spring
Molecular genetic principles: plasmid construction, purification, and characterization; PCR; mutageneses; hybridization and sequence analysis; protein quantitation; immunologic detection, and electrophoresis. Cross-listed as MBB 445. Credit is allowed for only MBB 445 or MIC 445. Prerequisites: both BIO 340 and MIC 302 or only instructor approval.

MIC 446 Techniques in Molecular Biology/Genetics Lab. (2)
fall and spring
Molecular genetic techniques; plasmid construction, purification, and characterization; PCR; mutageneses; hybridization and sequence analysis; protein quantitation; immunologic detection, and electrophoresis. Cross-listed as MBB 446. Credit is allowed for only MBB 446 or MIC 446. Pre- or corequisite: MBB 445 or MIC 445.

MIC 470 Bacterial Diversity and Systematics. (4)
fall
Biology, classification, and enrichment culture of the nonpathogenic bacteria. 2 hours lecture, 6 hours lab. Fee. Prerequisite: MIC 302.

MIC 485 General Virology. (3)
fall
Fundamental nature of viruses, their replication, pathogenesis, and ecology. Prerequisites: both BIO 340 and CHM 331 or only instructor approval.

MIC 486 General Virology Laboratory. (2)
not regularly offered
Fundamentals of virus detection, isolation and assay; propagation of virus in mammalian cell culture; recombinant virus and vector construction. 6 hours lab. Prerequisite: MIC 302. Pre- or corequisite: MIC 485.

MIC 494 Special Topics. (1–4)
not regularly offered
Possible topics:

(a)	Clinical Bacteriology Laboratory. (3)

MIC 495 Undergraduate Research. (1–6)
fall, spring, summer
Supervised research in microbiology. May be repeated for credit. Lab. Prerequisites: MIC 206, 220, 302; instructor approval.

MIC 527 Neuroimmunology. (3)
spring in odd years
Studies mind’s influence on immunity and the immune system’s influence on the mind, neuroimmunologic diseases, and the neuroimmunological circuitry involved. Seminar. Prerequisite: MIC 420 or instructor approval.

MIC 581 Molecular Mechanism of Pathogenesis. (3)
not regularly offered
Pathogenic mechanisms and host responses in viral and/or bacterial diseases. Prerequisites: both MIC 381 and 420 or only instructor approval.

MIC 585 Molecular Virology. (3)
not regularly offered
Selected topics concerning molecular aspects of eukaryotic virus replication and pathogenesis. Prerequisite: instructor approval.

MIC 591 Seminar. (1–12)
fall and spring
Possible topics:

(a)	Bacterial Ecology. (1–3)
(b)	Current Research in Microbiology. (1–3)
(c)	Enzymology. (1–3)
(d)	Genetic Engineering. (1–3)
(e)	Genetics. (1–3)
(f)	Immunology. (1–3)
(g)	Molecular Virology. (1–3)
(h)	Neuroimmunology. (1–3)
(i)	Pathogenic Bacteriology. (1–3)

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